In 2008, VGTI Florida® was created from a $60 million grant from the State of Florida Innovation Incentive Fund. Additional matching contributions from the City of Port St. Lucie and St. Lucie County were invested in infrastructure such as roads and utilities to allow the construction of the research facility at the Tradition Center for Innovation. The City of Port St. Lucie then supported a bond offering in 2010 by VGTI Florida of $50 million to fund the construction of a nearly 100,000 sq ft. facility nearby the Torrey Pines Institute for Molecular Studies and the new medical campus of Martin Health System.
VGTI Florida has over $20 million in grant support to fund the scientific research underway at the institute. Continued funding and support for the research at VGTI Florida comes mainly from granting agencies such as the National Institutes of Health, corporate sponsored research, and foundations such as the Gates Foundation. However, while these funds go to directly support the research activities at VGTI Florida they cannot be used to fund public outreach and educational activities sponsored by VGTI Florida. These activities require the philanthropic support from generous citizens, foundations, and corporate partners.